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Brefeldin A (from Penicillium brefeldianum)

Catalog number:  B7450

Related applications:

Cell Structure

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Description

The fungal metabolite brefeldin A (BFA) has multiple targets in cells and has proven valuable for dissecting the cellular processes, including vesicle formation and kinesin distribution, involved in exporting newly synthesized proteins. We are pleased to offer the natural brefeldin A isolated from Penicillium brefeldianum. Exposing cells to BFA causes a distortion in intracellular protein traffic from the ER to the Golgi apparatus and the eventual loss of Golgi apparatus morphology; removal of BFA completely reverses these effects. BFA also alters the morphology of endosomes and lysosomes.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Shipping Condition: Room Temperature
Label Type: Unlabeled
Product Type Specs: Sphingolipids
Recommended Storage: Store in freezer (-5 to -30°C).