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Thermo Scientific™
Orbitrap™ Excedion™ Series Hybrid Mass Spectrometers
Expand your analytical horizons with Orbitrap Excedion MS for small-molecule MetID, Metabolomics/Lipidomics and EFS Research. Upgradeable in-lab to Orbitrap Excedion Pro MS for more advanced proteomics and biopharma analysis.
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| Catalog Number | Model |
|---|---|
| BRE725574 | Orbitrap Excedion BioPharma Mass Spectrometer with mass range up to 8,000 |
| BRE725570 | Orbitrap Excedion Pro Mass Spectrometer with EASY-ETD ion source for metabolomics, lipidomics, proteomics, and structural biology |
| BRE725571 | Orbitrap Excedion Pro BioPharma Mass Spectrometer |
| BRE725572 | Orbitrap Excedion Pro Mass Spectrometer for metabolomics, lipidomics, proteomics, and structural biology |
| BRE0067126 | Factory installed Electron Transfer Dissociation (ETD) |
| BRE0065480 | Field upgrade Electron Transfer Dissociation (ETD) |
| BRE725573 | Orbitrap Excedion Mass Spectrometer for MetID, Metabolomics, Proteomics and EFS research |
Catalog number BRE725574
Price (USD)
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Model:
Orbitrap Excedion BioPharma Mass Spectrometer with mass range up to 8,000
Experience confident small-molecule and multi-omics analysis in complex samples. Accelerate insights across metabolomics, drug metabolism, and environmental research with Orbitrap Excedion MS, a versatile high-resolution accurate-mass platform that delivers high sensitivity, extended dynamic range with eDR, and sub-ppm mass accuracy. Orbitrap Excedion MS can be upgraded in-lab to Orbitrap Excedion Pro MS, expanding capabilities for advanced proteomics and biopharma research, including extended mass detection up to m/z 12,000 with optional fast and sensitive ETD/EThcD fragmentation.
Metabolomics
Orbitrap Excedion MS enables deep metabolomic profiling with high sensitivity, extended dynamic range (eDR), and HRAM performance. Fast polarity switching, nano-flow capabilities, and integrated Compound Discoverer workflows support broad coverage, including single-cell lipidomics.
Metabolite Identification (MetID)
For MetID, Orbitrap Excedion MS combines HRAM and eDR to detect low-abundance metabolites alongside parent compounds. Sub-ppm mass accuracy and integrated workflows with Thermo Scientific™ Compound Discoverer Software and Mass MetaSite™ enable confident annotation.
Environmental & Food Safety (EFS)
Orbitrap Excedion MS delivers sensitive EFS research analysis with enhanced MS1sensitivity and eDR for trace-level detection. HRAM full-scan data supports confident suspect and non-target screening of PFAS and emerging contaminants.
BioPharma
Orbitrap Excedion BioPharma edition MS supports BioPharma analysis through a dedicated oligonucleotide mode with optimized pressure control, enabling intact mass, sequencing, and quantitative characterization of mRNA, oligonucleotides, and ADC-related species.
With in-lab upgrade to Orbitrap Excedion Pro BioPharma edition MS and optional fast and sensitive ETD fragmentation, users can expand biopharma and proteomics capabilities. Advanced fragmentation enables Asp/IsoAsp detection, Leu/Ile resolution, enhanced middle-down coverage, and near single-residue HDX-MS, supporting deep proteome, PTM, and immunopeptidomics analysis.
Specifications
Detection Limits
- Full Scan: <1.5 fg reserpine on column
- MS 2 : <1.5 fg reserpine on column
- SIM: <0.8 fg reserpine on column
Dimensions (D x W x H)535 x 758 x 703 mm (21 x 29.8 x 27.7 in.)
Dynamic Range5 orders of magnitude within an eDR mode scan Orbitrap mass analyzer spectrum
FragmentationHigher Collisional Dissociation (HCD) for b/y ion fragmentation is included as standard.
Mass Accuracy
- 1-point calibration for <3 ppm RMS drift over at least 4 weeks*
- Internal lock mass calibration for <1 ppm RMS drift over 24 hours* EASY-IC for <1 ppm RMS drift for at least 5 days*
ModelOrbitrap Excedion BioPharma Mass Spectrometer with mass range up to 8,000
MultiplexingUp to 20 precursor ions per scan
Mass Range40 to 6000 m/z
Max. ResolutionUp to 240,000 at 200 m/z
TypeOrbitrap LC-MS
Unit SizeEach