5-TAMRA (5-Carboxytetramethylrhodamine), single isomer

Tetramethylrhodamine (TMR, TRITC) has been a widely used fluorophore for preparing bioconjugates, especially fluorescent antibody and avidin derivatives used in immunochemistry. Under the name TAMRA, the carboxylic acid of 5-TAMRA has also achieved prominence as a dye for oligonucleotide labeling and automated DNA sequencing applications.