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      ER-Tracker™ Red (BODIPY™ TR Glibenclamide), for live-cell imaging

      ER-Tracker™ Red (BODIPY™ TR Glibenclamide), for live-cell imaging

      Catalog number:  E34250

       Related applications: Cell Structure | Cell Tracing & Tracking | Cellular Imaging

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      Description

      ER-Tracker™ Red dye is cell-permeant, live-cell stain that is highly selective for the endoplasmic reticulum (ER) that when stained using the protocol provided, the staining pattern is partially retained after fixation with formaldehyde. This stain consists of the green-fluorescent BODIPY® TR dye and glibenclamide. Glibenclamide (glyburide) binds to the sulphonylurea receptors of ATP-sensitive K+ channels which are prominent on ER; the pharmacological activity of glibenclamide could potentially affect ER function. Variable expression of sulphonylurea receptors in some specialized cell types may result in non-ER labeling.
      For Research Use Only. Not for use in diagnostic procedures.

      Specifications

      Sub-Cellular Localization: Endoplasmic Reticulum
      Color: Red
      For Use With (Equipment): Fluorescence Microscope
      Detection Method: Fluorescent
      Excitation⁄Emission (nm): 587⁄615
      Product Line: BODIPY™, ER-Tracker™
      Product Size: 100 µg
      Shipping Condition: Room Temperature

      Contents & storage

      Store in freezer (-5 to -30°C) and protect from light.

      Documents

      Manuals & protocols