ER-Tracker™ Red dye is cell-permeant, live-cell stain that is highly selective for the endoplasmic reticulum (ER) that when stained using the protocol provided, the staining pattern is partially retained after fixation with formaldehyde. This stain consists of the green-fluorescent BODIPY® TR dye and glibenclamide. Glibenclamide (glyburide) binds to the sulphonylurea receptors of ATP-sensitive K+ channels which are prominent on ER; the pharmacological activity of glibenclamide could potentially affect ER function. Variable expression of sulphonylurea receptors in some specialized cell types may result in non-ER labeling.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Color
Red
Excitation Wavelength Range
587⁄615
For Use With (Equipment)
Fluorescence Microscope
Detection Method
Fluorescent
Product Line
BODIPY™, ER-Tracker™
Shipping Condition
Room Temperature
SubCellular Localization
Endoplasmic Reticulum
Contents & Storage
Store in freezer -5°C to -30°C and protect from light.
Figures
Tubulin in a live bovine pulmonary artery endothelial cell labeled with TubulinTracker™ Green reagent.
