Invitrogen™

Guanosine 5'-O-(3-Thiotriphosphate), BODIPY™ FL Thioester, Sodium Salt (BODIPY™ FL GTP-γ-S, Thioester)

Catalog number:  G22183

Related applications:

Protein Assays and Analysis

| Pharma & Biopharma

Back to top

Description

BODIPY FL GTP-γ-S binds to GTP-binding proteins. To create this fluorescent nucleotide, the BODIPY FL fluorophore was linked through the γ-thiol of GTP-γ-S. The fluorescence of BODIPY FL GTP-γ-S is quenched ~90% relative to that of the free dye, but may be recovered on binding to G-proteins. In addition to its potential use for binding studies, the BODIPY FL GTP-γ-S thioether is an important new substrate for Fhit, a member of the histidine triad superfamily of nucleotide-binding proteins.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Concentration: 5 mM
Labeling Method: Chemical Labeling, Direct Labeling
Shipping Condition: Wet Ice
Product Line: BODIPY™
Label or Dye: BODIPY® FL
Label Type: BODIPY Dyes

Contents & storage

Store in freezer (-5 to -30°C) and protect from light.