Gibco™

Human NTCP (G) SLC Transporter Cells

Catalog number: GM1113G
Gibco™

Human NTCP (G) SLC Transporter Cells

Catalog number: GM1113G
Catalog Number
GM1113G
Unit Size
8–10M cells
Price (USD)
538.00
Your Price:
Availability
***
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
GM1113G8–10M cells
538.00
Your Price:
***
Product Overview
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TRANSiPORT Human NTCP (G) SLC Transporter Cells are HEK293 cells that transiently overexpress the NTCP solute carrier (SLC) transport protein. Solute carriers are a super-family of membrane transporters that can affect pharmacokinetics and drug exposure by governing the transport of solutes in and out of cells. The NTCP SLC transporter protein is found in hepatocytes.

• Assess potential for transporter-mediated drug metabolism
• Easy to use format
• Obtain high quality results with a large signal-to-noise ratio

Choice of measurement system
Cell-based assays can be performed using radioisotope-labeled compounds, fluorescence-labeled compounds, or non-labeled compounds. The amount of substrate transported into the cells can be measured directly using a liquid scintillation counter, fluorescence plate reader, or LC-MS/MS, thereby allowing direct evaluation of SLC transporter activity.

Assay reliability
Mock HEK293 cells (Cat. No. GM1101G) that do not overexpress the SLC transporter are available for use as a negative experimental control. Some compounds may demonstrate high background levels of transport due to the presence of endogenous transporters or non-specific binding.

Rapid results
The convenient product format enables data generation in 2 days from thawing of the cells to final results.

Related products
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GM1103G Human OAT1 (G) SLC Transporter Cells
GM1104G Human OAT3 (G) SLC Transporter Cells
GM1105G Human OCT2 (G) SLC Transporter Cells
GM1106G Human OATP1B3 (G) SLC Transporter Cells
GM1108G Human OCT1 (G) SLC Transporter Cells
GM1114G Human MATE1 (G) SLC Transporter Cells
GM1115G Human MATE2K (G) SLC Transporter Cells
GM1101G Mock Cells

Specifications

Cell Type
HEK293
Culture Type
Mammalian Cell Culture
Species
Human
Type
SLC Transporter Cell
Quantity
8 to 10M cells

Contents & Storage

Store in liquid nitrogen vapor phase.

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