3-Hydroxyazetidine hydrochloride is an building block used in a recent synthesis of a fluoroquinolone antibiotic and a useful intermediate in the synthesis of polypeptides.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Aplicaciones
El clorhidrato de 3-hidroxiazetidina es un compuesto básico que se ha utilizado en la síntesis reciente de un antibiótico de fluoroquinolona y un intermedio útil en la síntesis de polipéptidos.
Solubilidad
Soluble en agua, DMSO y metanol.
Notas
Higroscópico. Almacenar en gas inerte. Almacenar alejado del agua, la humedad y agentes oxidantes.
RUO - Para uso exclusivo en investigación
General References:
- Paritosh R. Dave. Acylative Dealkylation of N-tert-Butyl-3-substituted Azetidines: Facile Access to [1.1.0]Azabicyclobutane, 3-Hydroxyazetidinium Hydrochloride, and 3-Azetidinones. J. Org. Chem. 1996, 61 (16), 5453-5455.
- Stephen D. Roughley; Terance Hart. Fatty acid amide hydrolase inhibitors. 2. Novel synthesis of sterically hindered azabenzhydryl ethers and an improved synthesis of VER-156084. Tetrahedron Letters. 2010, 51 (39), 5191-5194.