It is a reactant involved in the synthesis of substrates for tin tetrachloride mediated fragmentation to produce ynones and ynoates, tandem oxidation coupling reactions with diamines, asymmetric allylic alkylation of enolates and formate reduction of allylic carbonates for polypropionate systems.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
It is a reactant involved in the synthesis of substrates for tin tetrachloride mediated fragmentation to produce ynones and ynoates, tandem oxidation coupling reactions with diamines, asymmetric allylic alkylation of enolates and formate reduction of allylic carbonates for polypropionate systems.
Solubility
Partly miscible in water.
Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Keep away from ignition sources. Protect from electrostatic charges. Ensure adequate ventilation.
RUO – Research Use Only
Barry M Trost, et al. Enantioselective synthesis of alpha-tertiary hydroxyaldehydes by palladium-catalyzed asymmetric allylic alkylation of enolates.J Am Chem Soc.,2009,129(2), 282-3.
Ali Bayir, et al. Preparation of tethered aldehyde ynoates and ynones by ring fragmentation of cyclic gamma-oxy-beta-hydroxy-alpha-diazo carbonyls.J Org Chem.,2010,75(2), 296-302.