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5-Bromo-2'-deoxyuridine, 99%, Thermo Scientific Chemicals
Catalog number: H27260.06
5 g, Each
Thermo Scientific Chemicals
5-Bromo-2'-deoxyuridine, 99%, Thermo Scientific Chemicals
Catalog number: H27260.06
5 g, Each
Quantity
Catalog number: H27260.06
also known as H27260-06
Price (USD)
Price: 373.00
Online price: 317.65
Your price:
Quantity
-
Chemical Identifiers
CAS
59-14-3
IUPAC Name
5-bromo-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
Molecular Formula
C9H11BrN2O5
InChI Key
WOVKYSAHUYNSMH-RRKCRQDMSA-N
SMILES
OC[C@H]1O[C@H](C[C@@H]1O)N1C=C(Br)C(=O)NC1=O
Specifications
Specification SheetAppearance (Color)
White to pale cream
Assay (HPLC)
≥98.5%
Optical Rotation
+31.0 ± 1.5? (c=1 in 0.1N NaOH) or +23.0 ± 1? (c=1 in water)
Form
Crystals or powder or crystalline powder
Identification (FTIR)
Conforms (UK sourced product only)
Description
5-Bromo-2'-deoxyuridine (BrdU) is a thymidine analog used to label DNA. It is incorporated into newly synthesized DNA in place of thymidine during the S phase of the cell cycle. Cells that were actively proliferating can then be detected by denaturing the DNA and allowing specific antibodies to target the BrdU incorporation. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
5-Bromo-2′-deoxyuridine (BrdU) is a thymidine analog used to label DNA. It is incorporated into newly synthesized DNA in place of thymidine during the S phase of the cell cycle. Cells that were actively proliferating can then be detected by denaturing the DNA and allowing specific antibodies to target the BrdU incorporation. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation.
Solubility
Soluble in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
5-Bromo-2′-deoxyuridine (BrdU) is a thymidine analog used to label DNA. It is incorporated into newly synthesized DNA in place of thymidine during the S phase of the cell cycle. Cells that were actively proliferating can then be detected by denaturing the DNA and allowing specific antibodies to target the BrdU incorporation. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation.
Solubility
Soluble in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
RUO – Research Use Only
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