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![6-Bromopyrazolo[1,5-a]pyrimidine, 97%](/TFS-Assets/CCG/Chemical-Structures/chemical-structure-cas-705263-10-1.jpg-650.jpg)
![6-Bromopyrazolo[1,5-a]pyrimidine, 97%](/TFS-Assets/CCG/Chemical-Structures/chemical-structure-cas-705263-10-1.jpg-150.jpg)
![6-Bromopyrazolo[1,5-a]pyrimidine, 97%](/TFS-Assets/CCG/logos/Thermo-Scientific-Stacked.jpg-150.jpg)
Thermo Scientific Chemicals
6-Bromopyrazolo[1,5-a]pyrimidine, 97%
CAS: 705263-10-1 | C6H4BrN3 | 198.02 g/mol
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Catalog number H33855.03
also known as H33855-03
Price (EUR)
81,10
Each
Quantity:
1 g
Price (EUR)
81,10
Each
Chemical Identifiers
CAS705263-10-1
IUPAC Name6-bromopyrazolo[1,5-a]pyrimidine
Molecular FormulaC6H4BrN3
InChI KeyVDHTXLUCUNPVLO-UHFFFAOYSA-N
SMILESBrC1=CN2N=CC=C2N=C1
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Specifications
Specification Sheet
Specification SheetFormCrystals or powder or crystalline powder or flakes
Melting Point (clear melt)119.0-128.0?C
Assay (GC)≥96.0%
Appearance (Color)Pale yellow to yellow to pale orange
6-Bromopyrazolo[1,5-a]pyrimidine is a reactant in the synthesis of LDN-212854, a selective and potent inhibitor of the BMP type I receptor kinases.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
6-Bromopyrazolo[1,5-a]pyrimidine is a reactant in the synthesis of LDN-212854, a selective and potent inhibitor of the BMP type I receptor kinases.
Solubility
Slightly soluble in water.
Notes
Light Sensitive. Store in dark. Store away from oxidizing agent.
6-Bromopyrazolo[1,5-a]pyrimidine is a reactant in the synthesis of LDN-212854, a selective and potent inhibitor of the BMP type I receptor kinases.
Solubility
Slightly soluble in water.
Notes
Light Sensitive. Store in dark. Store away from oxidizing agent.
RUO – Research Use Only
General References:
- Agustin H. Mohedas; Xuechao Xing; Kelli A. Armstrong; Alex N. Bullock; Gregory D. Cuny; and Paul B. Yu. Development of an ALK2-Biased BMP Type I Receptor Kinase Inhibitor. ACS Chem. Biol. 20138 (6), 1291-1302
- Mingshan Gao; Lei Duan; Jinfeng Luo; Lianwen Zhang; Xiaoyun Lu; Yan Zhang; Zhang Zhang; Zhengchao Tu; Yong Xu; Xiaomei Ren; and Ke Ding. Discovery and Optimization of 3-(2-(Pyrazolo[1,5-a]pyrimidin-6-yl)ethynyl)benzamides as Novel Selective and Orally Bioavailable Discoidin Domain Receptor 1 (DDR1) Inhibitors. J. Med. Chem. 201356 (8), 3281-3295