3,4-Difluorophenylmagnesium bromide, 0.50 M in 2-MeTHF is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff fields.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
3,4-Difluorophenylmagnesium bromide, 0.50 M in 2-MeTHF is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff fields.
Solubility
Reacts with water.
RUO – Research Use Only
General References:
- Yunxiang Chen; Yangwei Huang; Xueqing Zhao; & Zhongming Lia. Concise Synthesis of 1,3-Diacetoxy-2-[2'-(2'',4''-difluorophenyl)prop-2'-en-1'-yl]propane: An Intermediate for Posaconazole. Synthetic Communications: An International Journal for Rapid Communication of Synthetic Organic Chemistry. 2015, 45 (6), 734-740.
- Timothy A. Shepherd; James A. Aikins; David Bleakman; Buddy E. Cantrell; John P. Rearick; Richard L. Simon; Edward C. R. Smith; Gregory A. Stephenson; and Dennis M. Zimmerman. Design and Synthesis of a Novel Series of 1,2-Disubstituted Cyclopentanes as Small, Potent Potentiators of 2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propanoic Acid (AMPA) Receptors. J. Med. Chem. 2002, 45 (10), 2101-2111.