HybriType™ sets itself apart with its hybrid capture technology, enabling robust performance while simultaneously simplifying the workflow process. Sequence 18 loci, covering HLA (classical and non-classical) and MIC genes from blood or buccal sample extracted DNA. Its exceptional design delivers consistent and reliable high-resolution results across all loci on day 2. All reagents necessary for genomic library preparation and hybrid capture enrichment are included with this high-resolution NGS genotyping assay.
Simplified workflow
- Support DNA from whole blood or buccal swabs across a wide input range with ready-to-use reagents.
- Minimize hands-on time through single-step fragmentation, repair, and adenylation, one-step barcoding, and simplified post-capture washes
Flexible, modular genotyping
- Choose between two targeted panels: one for 11 classical HLA loci and another for 7 non-classical MHC loci.
- Easily expand testing to include ABO typing with the HybriType™ ABO Flex Panel – 4 Enrichments, or maintain workflow continuity using the HybriType™ HLA Plus 18 Loci Flex Kit – 4 Enrichments when enrichment reagents run low.
Quality results
- Mitigate PCR amplification bias and produce consistent balanced reads using target specific capture probes inherent to the HybriType™ NGS strategy
Improved data quality
- Achieve uniform, well-balanced data with hybrid capture–based targeted enrichment, while UDI indexing minimizes barcode hopping and misassignment
Expand Understanding
Advance insight into the relationship between allele balance and zygosity with reported copy number values