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Zitierungen und Referenzen (14)
Invitrogen™
Image-IT™ LIVE Assay-Kit für die mitochondriale Transitionspore, für die Mikroskopie
Das Image-iT™ LIVE Mitochondrial Transition Pore Assay Kit bietet eine bewährte Methode [REF PN36389, PN32679] zur Messung der Porenöffnung mitochondrialerWeitere Informationen
| Katalognummer | Menge |
|---|---|
| I35103 | 1 Kit |
Katalognummer I35103
Preis (EUR)
944,24
Sonderangebot
Exklusiv online
Endet: 15-Mar-2026
1.276,00Ersparnis 331,76 (26%)
Each
Menge:
1 Kit
Preis (EUR)
944,24
Sonderangebot
Exklusiv online
Endet: 15-Mar-2026
1.276,00Ersparnis 331,76 (26%)
Each
Das Image-iT™ LIVE Mitochondrial Transition Pore Assay Kit bietet eine bewährte Methode [REF PN36389, PN32679] zur Messung der Porenöffnung mitochondrialer Membrandurchgängigkeit. Das Kit enthält einen Farbstoff und einen Quencher, die problemlos in Zellen geladen werden können. In gesunde Zellen gelangt der Farbstoff, nicht jedoch der Quencher, in Mitochondrien. Die Mitochondrien bleiben hell fluoreszierend, bis die Aktivierung der mitochondrialen Pore ein Quenchen der Fluoreszenz ermöglicht.
Nur für Forschungszwecke. Darf nicht für diagnostische Verfahren eingesetzt werden.
Specifications
FarbeOrange, Blau, Grün
Zur Verwendung mit (Geräte)Fluoreszenzmikroskop
ProduktlinieImage-iT
ProdukttypMitochondrien-Transitionsporen-Assay-Kit
Menge1 Kit
VersandbedingungRaumtemperatur
Subzelluläre LokalisationMitochondrien
FormatKit
Unit SizeEach
Inhalt und Lagerung
Bei -5 bis -30 °C lagern und vor Licht schützen.
Zitierungen und Referenzen (14)
Zitierungen und Referenzen
Abstract
Transient and long-lasting openings of the mitochondrial permeability transition pore can be monitored directly in intact cells by changes in mitochondrial calcein fluorescence.
Journal:Biophys J
PubMed ID:9929477
'The occurrence and the mode of opening of the mitochondrial permeability transition pore (MTP) were investigated directly in intact cells by monitoring the fluorescence of mitochondrial entrapped calcein. When MH1C1 cells and hepatocytes were loaded with calcein AM, calcein was also present within mitochondria, because (i) its mitochondrial signal was
Effect of transient and permanent permeability transition pore opening on NAD(P)H localization in intact cells.
Journal:J Biol Chem
PubMed ID:19346250
'To study the effect of mitochondrial permeability transition pore (PTP) opening on NAD(P)H localization, intact cells were exposed to the Ca(2+) ionophore A23187. PTP opening, mitochondrial membrane potential, mitochondrial volume, and NAD(P)H localization were assessed by time-lapse laser confocal microscopy using the calcein-cobalt technique, tetramethylrhodamine methyl ester, MitoTracker, and NAD(P)H
Measuring apoptosis at the single cell level.
Journal:Methods
PubMed ID:18314052
The use of live cell microscopy has made a number of contributions to the study of apoptosis. Many of the tools and techniques are available that allow us to image the key events that occur during cell death including mitochondrial outer membrane permeabilization, mitochondrial transmembrane potential changes, translocation of Bcl-2
The mechanisms of apoptosis in biology and medicine: a new focus for ophthalmology.
Journal:Eur J Ophthalmol
PubMed ID:12749672
Defects in apoptosis (programmed cell death) have recently emerged as being closely involved in the pathogenesis of most ocular diseases and, therefore, apoptosis is now a topic of exponential interest in ophthalmology. This review summarizes recent works on mechanisms of apoptosis, from its initiation and modulation to the switching-on of
Therapeutic Potential of a Novel Necrosis Inhibitor, 7-Amino-Indole, in Myocardial Ischemia-Reperfusion Injury.
Journal:Hypertension
PubMed ID:29661840