Recommended Use:

• For laboratories supporting life science, drug discovery and development research or high-throughput screening and clinical testing.
• In combination with Thermo Scientific mass spectrometers, the Open Sampler XRS system shows exceptional capabilities for LC/MS workflows employing 1 to 4.6 mm internal column diameters.
• It is ideal for comparative studies such as in metabolomics, authenticity or toxicity screening; discovery of new therapeutically active substances; forensics; in-depth nutritional studies; and food safety investigations.
• You can achieve lower detection limits, monitor the UV signal of samples without noticeable resolution loss and produce more high-quality, information-rich data in less time.

Ensuring Excellent Chromatography:

• Up to 2 mL/min. flow rate supports up to 125 MPa (1250 bar) (18,250 psi) backpressure for fast and highly resolving column technologies.
• A quaternary gradient UHPLC pump offers gradient delay volumes as little as 200 µL for fast gradient response.
• Spacious and shared column compartment keeps columns and samples at constant temperature (5° to 110°C) for improved retention time precision.
• Advanced flow technology offers precise and accurate flow rates for stable retention times, robust peak integration and confident identification.
• The Thermo Scientific™ Dionex™ Viper™ Fingertight fitting system offers near-zero dead volume for optimal peak shapes even over extended periods.
• Ultra-low carryover, large sample capacity (pull loop, up to 12 well plates) Open Sampler maximizes throughput with unattended operation.
• Adjustable gradient delay volumes using Thermo Scientific™ SpinFlow™ technology optimizes mixing efficiency.

Chromeleon CDS Software Makes Operation Easy:

• Integrated service and validation monitoring with Thermo Scientific™ Dionex™ Chromeleon™ CDS software, versions 6.x and 7.x
• Automated system startup, standby and shutdown with Chromeleon CDS software, versions 6.x and 7.x
• Compatible with Chromeleon 7.x eWorkflow walk-up solution and advanced reporting features

Choose the Right Configuration for You:

• Four-solvent channel, quaternary pump with built-in degasser for versatile gradient methods (LPG-3400XRS)
• Thermostatted or nonthermostatted Open Autosamplers (OAS-3300TXRS, OAS-3600TXRS)
• Thermostatted column compartment with up to two field-upgradable column switching valves (TCC-3000RS)
• Diode array, multiple wavelength, variable wavelength, fluorescence, charged aerosol, refractive index or mass spectrometry detectors [all linked, RS types if applicable]
• New, near-zero peak dispersion UV monitor flow cell (45 nL cell volume, for VWD-3x00 series)
• Chromeleon 7.2 software packages (standalone, networked, remote data processing and/or control)