LTQ Orbitrap XL™ Hybrid Ion Trap-Orbitrap Mass Spectrometer

Thermo Scientific™  Related applications: Industrial Mass Spectrometry

Perform a range of applications from protein identification, to biomarker discovery, de novo sequencing and metabolite profiling, with confidence. The Thermo Scientific™ LTQ Orbitrap XL™ Hybrid Ion Trap-Orbitrap Mass Spectrometer is a Fourier Transform Mass Spectrometer (FTMS) based on Thermo Scientific™ LTQ XL™ linear ion trap and Orbitrap mass spectrometer technologies. To enhance the flexibility of fragmentation experiments for advanced proteomics and small molecule research, the instrument features an HCD collision cell.

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Protein Identification
  • High mass accuracy lowers false positive rates
  • Parallel acquisition mode optimizes productivity
  • High MS and MS/MS sensitivity, wide dynamic range and fast cycle times increase protein identifications

Biomarker Discovery

  • HCD collision cell provides high fragmentation efficiency combined with high sensitivity for the reporter and fragment ions of the peptide sequence
  • Reliable identification and quantification in one experiment

De novo Sequencing

  • High mass accuracy and high resolution leads to high confidence de novo sequencing results
  • Multiple collision modes (CID and HCD) provide comprehensive structural information

Metabolite Profiling and Identification

  • High mass accuracy, sensitivity, and dynamic range enable reliable profiling of low-abundance metabolites in complex mixtures
  • MSn spectral tree fingerprints distinguish between isobaric compounds
  • Thermo Scientific™ SIEVE™ and Mass Frontier™ software facilitate determination of differentially expressed metabolites
  • Thermo Scientific™ MetWorks™ and Mass Frontier software automates structural elucidation

Application Software

  • Thermo Scientific™ MetWorks, Mass Frontier, PEAKS™, ProMass™ Deconvolution, ProsightPC, Proteome Discoverer™ and SIEVE software are available to increase data analysis productivity.
For research use only. Not for use in diagnostic procedures.

Access to our expert service team, information on support plans, parts and consumables resources, and other instrument services.  USA only [EN]

From routine to research

From routine compound identification to the most challenging analysis of low-level components in complex mixtures, the LTQ Orbitrap XL hybrid ion trap-Orbitrap mass spectrometer supports the widest ranges of applications.

  Meet the widest range of challenges ›


Manuals & protocols