Thermo Scientific™

ScreenID™ HRAM™ LC-MS System for Forensic Toxicology and Clinical Research

 Related applications:
Industrial Mass Spectrometry
Close your uncertainty gap with HRAM (high-resolution accurate-mass) spectrometry. Today's forensic toxicology and clinical research laboratory demands more application versatility, data accuracy, and value from the LC-MS systems used for targeted compound screening, quantitation, metabolite identification, as well as the ability to identify true unknown compounds.

Confident unknown identification, compound screening, confirmation, and quantification is easier and more affordable than ever before. The value-priced, industry-proven Thermo Scientific™ ScreenID™ HRAM™ system bundle is built on the Thermo Scientific™ Q Exactive™ Focus hybrid quadrupole-Orbitrap mass spectrometer, Thermo Scientific™ Dionex™ UltiMate™ 3000 RSLC system, and the Thermo Scientific™ High-Resolution Accurate-Mass MS/MS Spectral Libraries.


The ScreenID HRAM system is a value-priced, robust and reliable solution built on the proven Thermo Scientific™ Q Exactive™ Focus hybrid quadrupole-Orbitrap MS, Thermo Scientific™ High-Resolution Accurate-Mass MS/MS Spectral Libraries and Thermo Scientific™ TraceFinder™ and ToxFinder™ software. Confident unknown identification, screening, confirmation and quantification is easier and more affordable than ever before.

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Description

Why do you need HRAM?

High resolution and mass accuracy are important for improving analytical sensitivity, data selectivity, and accuracy in analysis of biological matrices. Furthermore, high-resolution accurate-mass analytical methods minimize false detection for analytes of interest and improve confidence in identification of known and unknown compounds. Accurate quantitation relies on resolving the compound of interest from complex biological matrix, and high resolving power will make the difference between detecting and not detecting analytes at low concentrations due to the masking effect of isobaric interferences.


While Time-of-flight (TOF) technology has also been long used for compound screening and quantitation, can suffer from lower dynamic range, inadequate resolution and mass accuracy (requires a lock mass) and therefore limited selectivity. Limited selectivity results in increased matrix interferences, causing false detection of analytes of interest and inaccurate quantitation. The Screen ID HRAM system bundle includes a proven combination of HRAM mass spectrometer and UHPLC designed to deliver forensic and clinical research application versatility and superior performance. With the combination of stable mass calibration, low maintenance requirements, unmatched flow rate range and simple method development, the ScreenID HRAM system provides a reliable, easy-to-use solution for forensic and clinical research lab work. Easily acquire answers - from method design to data analysis


Acquire answers easily, from analytical method design to data analysis

ScreenID HRAM includes two software solutions — Thermo Scientific™ ToxFinder™ easy-to-use data processing software with streamlined workflows for targeted compound screening applications, and Thermo Scientific™ TraceFinder™ software, which provides a flexible workflow-driven method setup with fully automated data acquisition, data processing, and reporting for a wide range of applications including quantitation, targeted and unknown unknown compound screening applications.


Maximize productivity - set up forensic and clinical research applications readily

To speed deployment, the ScreenID HRAM system bundle includes three days of onsite training (North American only).


Identify a broad range of compounds rapidly

Identification of a broad range of compounds is faster and more reliable with the High-Resolution Accurate-Mass MS/MS Spectral Libraries. The libraries include multiple spectra of 2500 drugs of abuse, veterinary drugs, therapeutic drugs, environmental toxins and mycotoxins.



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Manuals & protocols