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Thermo Scientific Chemicals
Enalapril
Long-acting ACE inhibitor and antihypertensive | CAS: 75847-73-3 | C20H28N2O5 | 376.453 g/mol
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CAS75847-73-3
IUPAC Name(2S)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]pyrrolidine-2-carboxylic acid
Molecular FormulaC20H28N2O5
InChI KeyGBXSMTUPTTWBMN-XIRDDKMYSA-N
SMILESCCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O
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規格
規格表
規格表Appearance (Color)White
FormCrystals or powder or crystalline powder
Assay from Supplier's CofA≥98.0%
Enalapril is used in the treatment of hypertension, diabetic nephropathy, and some types of chronic heart failure. It has been proven to protect the function of the kidneys in hypertension, heart failure, and diabetes, and may be used in the absence of hypertension for its kidney protective effects. It is widely used in chronic kidney failure.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Enalapril is used in the treatment of hypertension, diabetic nephropathy, and some types of chronic heart failure. It has been proven to protect the function of the kidneys in hypertension, heart failure, and diabetes, and may be used in the absence of hypertension for its kidney protective effects. It is widely used in chronic kidney failure.
Solubility
Soluble in water at 25mg/ml
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, heat.
Enalapril is used in the treatment of hypertension, diabetic nephropathy, and some types of chronic heart failure. It has been proven to protect the function of the kidneys in hypertension, heart failure, and diabetes, and may be used in the absence of hypertension for its kidney protective effects. It is widely used in chronic kidney failure.
Solubility
Soluble in water at 25mg/ml
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, heat.
RUO – Research Use Only
General References:
- CONSENSUS Trial Study Group. Effects of enalapril on mortality in severe congestive heart failure : Results of the Cooperative North Scandinavian Enalapril Survival Study. N Engl J Med . 1987, 316 1429-1435.
- S. Yusuf, FRCP,;, C.J. Pepine, MD,; C. Garces, MSc,; H. Pouleur, MD,; M. Rousseau, MD,; D. Salem, MD,; J. Kostis, MD,; C. Benedict, MD,; M. Bourassa, MD. Effect of enalapril on myocardial infarction and unstable angina in patients with low ejection fractions . Journal name. 1992, 340, ( 8829), 1173-1178.