Search Thermo Fisher Scientific
Element Search
Structure SearchThermo Scientific Chemicals
Lincomycin hydrochloride, Thermo Scientific Chemicals
Catalog number: J61251.14
25 g, Each
Thermo Scientific Chemicals
Lincomycin hydrochloride, Thermo Scientific Chemicals
Catalog number: J61251.14
25 g, Each
Quantity
Catalog number: J61251.14
also known as J61251-14
Price (USD)
Price: 808.00
Your price:
Quantity
-
Chemical Identifiers
CAS
859-18-7
IUPAC Name
hydrogen (2S,4R)-N-[(1R,2R)-2-hydroxy-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylsulfanyl)oxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide chloride
Molecular Formula
C18H35ClN2O6S
InChI Key
POUMFISTNHIPTI-BOMBIWCESA-N
SMILES
[H+].[Cl-].CCC[C@@H]1C[C@H](N(C)C1)C(=O)N[C@H]([C@@H](C)O)[C@H]1O[C@H](SC)[C@H](O)[C@@H](O)[C@H]1O
Specifications
Specification SheetAppearance (Color)
White
Water Content (Karl Fischer Titration)
3.1-4.6%
Potency
≥ 790 µg/mg (anhydrous basis)
Optical Rotation
[α] = +135 to +150º
Form
Crystalline Powder
Description
Lincomycin hydrochloride is used to study the inhibition of protein synthesis, bacterial antibiotic resistance and protein and surfactant binding. It has been used in the treatment of Staphylococcal, Streptococcal, and Bacterioides fragilis infections.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
Lincomycin hydrochloride is a lincosamide compound with antibacterial activity originally identified in the actinomycete, Streptomyces lincolnensis, with activity against gram-positive cocci and anaerobic bacteria
Lincomycin inhibits bacterial protein synthesis by forming cross-links within the peptidyl transferase loop region of the 23S rRNA
Application
Lincomycin hydrochloride is commonly used to study the inhibition of protein synthesis, bacterial antibiotic resistance, and protein and surfactant binding
It has been used against Staphylococcal, Streptococcal, and Bacteroides fragilis species
It is protective against the development of mastitis in a mouse model of acute mastitis induced by S. aureus
RUO – Research Use Only
Figures
Documents & Downloads
Certificates
Search by lot number or partial lot number
Frequently asked questions (FAQs)
Citations & References
Search citations by name, author, journal title or abstract text