Thermo Scientific Chemicals

Neomycin sulfate hydrate, Thermo Scientific Chemicals

Catalog number: J61499.14
25 g, Each
Thermo Scientific Chemicals

Neomycin sulfate hydrate, Thermo Scientific Chemicals

Catalog number: J61499.14
25 g, Each
Quantity
Informational:Informational:This chemical may require us to obtain additional information for our regulatory and chemical compliance records. If required, we will contact you for this information once your order is placed.
Catalog number: J61499.14
also known as J61499-14
Price (USD)
Price: 47.40
Online price: 40.65
Your price:
Quantity
-

Chemical Identifiers

CAS
1405-10-3
IUPAC Name
5-amino-2-(aminomethyl)-6-{[(2R,3S,4R,5S)-5-[(3,5-diamino-2-{[3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy}-6-hydroxycyclohexyl)oxy]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxy}oxane-3,4-diol; sulfuric acid
Molecular Formula
C23H48N6O17S
InChI Key
OIXVKQDWLFHVGR-DJUBFIBWNA-N
SMILES
OS(O)(=O)=O.NCC1OC(O[C@@H]2[C@@H](CO)O[C@@H](OC3C(O)C(N)CC(N)C3OC3OC(CN)C(O)C(O)C3N)[C@@H]2O)C(N)C(O)C1O
Assay (unspecified)
Potency: 600 ?g/mg min.
Loss on Drying
8.0% max.

Description

Neomycin sulfate is an aminoglycoside antibiotic and calcium channel protein inhibitor. Neomycin sulfate also binds to prokaryotic ribosomes inhibiting translation and is effective against gram-positive and gram-negative bacteria. Neomycin sulfate inhibits Phospholipase C via binding to inositol phospholipids. It also inhibits phosphatidylcholine-PLD activity and induces Ca2+ mobilization and PLA2 activation in human platelets. Neomycin sulfate inhibits DNase I induced DNA degradation.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Neomycin sulfate is an aminoglycoside antibiotic and calcium channel protein inhibitor. Neomycin sulfate also binds to prokaryotic ribosomes inhibiting translation and is effective against gram-positive and gram-negative bacteria. Neomycin sulfate inhibits Phospholipase C via binding to inositol phospholipids. It also inhibits phosphatidylcholine-PLD activity and induces Ca2+ mobilization and PLA2 activation in human platelets. Neomycin sulfate inhibits DNase I induced DNA degradation.

Solubility
Soluble in water

Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
WARNING: Reproductive Harm - www.P65Warnings.ca.gov
RUO – Research Use Only

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