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Cyclosporin A, 99+%, Thermo Scientific Chemicals
Catalog number: J63191.03
1 g, Each
Thermo Scientific Chemicals
Cyclosporin A, 99+%, Thermo Scientific Chemicals
Catalog number: J63191.03
1 g, Each
Quantity
Catalog number: J63191.03
also known as J63191-03
Price (USD)
227.00
Each
Quantity
-
Chemical Identifiers
CAS
59865-13-3
Specifications
Specification SheetAppearance (Color)
White
Assay from Suppliers CofA
≥99.0%
Form
Powder or crystals or crystalline powder
Description
Ciclosporin A induces apoptosis and inhibits angiogenesis induced by VEGF. It also suppresses the replication of hepatitis C virus genome in cultured hepatocytes.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Cyclosporin A is a non-polar cyclic oligopeptide produced by the fungus Tolypocladium inflatum
Applications
• It inhibits phosphoprotein phosphatase
• Cyclosporin A binds to the cellular protein cytophilin and inhibits the enzyme calcineurin
• Furthermore, it can induce apoptosis and inhibit angiogenesis induced by VEGF
• It exerts potent immunosuppressive activity on T immune cells, and causes reversible inhibition of immunocompetent lymphocytes in the G0- and G1-phase of the cell cycle
• It also suppresses the hepatitis C virus replication in cultured hepatocytes
WARNING: Cancer – www.P65Warnings.ca.gov
RUO – Research Use Only
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