Thermo Scientific Chemicals

Bisindolylmaleimide 1, Thermo Scientific Chemicals

Catalog number: J63401.MB
25 mg, Each
Thermo Scientific Chemicals

Bisindolylmaleimide 1, Thermo Scientific Chemicals

Catalog number: J63401.MB
25 mg, Each
Quantity
Catalog number: J63401.MB
also known as J63401-MB
Price (USD)
Price: 482.00
Online price: 421.65
Your price:
Quantity
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Chemical Identifiers

CAS
133052-90-1
IUPAC Name
3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-(1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione
Molecular Formula
C25H24N4O2
InChI Key
QMGUOJYZJKLOLH-UHFFFAOYSA-N
SMILES
CN(C)CCCN1C=C(C2=CC=CC=C12)C1=C(C(=O)NC1=O)C1=CNC2=CC=CC=C12
Appearance (Color)
Red
Assay from Suppliers CofA
≥98%
Form
Powder or crystals or crystalline powder
Proton NMR
Conforms

Description

Bisindolylmaleimide is used as a highly selective inhibitor of all PKC isoforms and slight inhibitor of GSK-3, used to selectively probe for PKC-mediated pathways for transduction of hormone, cytokine, and growth factor signals, very potent and selective inhibitor of protein kinase C.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Bisindolylmaleimide is used as a highly selective inhibitor of all PKC isoforms and slight inhibitor of GSK-3, used to selectively probe for PKC-mediated pathways for transduction of hormone, cytokine, and growth factor signals, very potent and selective inhibitor of protein kinase C.

Solubility
Insoluble in water.

Notes
Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.
RUO – Research Use Only

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