Thermo Scientific Chemicals

Thiamphenicol, Thermo Scientific Chemicals

Catalog number: J63575.06
5 g, Each
Thermo Scientific Chemicals

Thiamphenicol, Thermo Scientific Chemicals

Catalog number: J63575.06
5 g, Each
Quantity
Informational:Informational:This chemical may require us to obtain additional information for our regulatory and chemical compliance records. If required, we will contact you for this information once your order is placed.
Catalog number: J63575.06
also known as J63575-06
Price (USD)
Price: 65.40
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Quantity
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Chemical Identifiers

CAS
15318-45-3
IUPAC Name
2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-methanesulfonylphenyl)propan-2-yl]acetamide
Molecular Formula
C12H15Cl2NO5S
InChI Key
OTVAEFIXJLOWRX-NXEZZACHSA-N
SMILES
CS(=O)(=O)C1=CC=C(C=C1)[C@@H](O)[C@@H](CO)NC(=O)C(Cl)Cl
Appearance (Color)
White to yellow
Sulfated Ash
≤0.5%
Assay from Suppliers CofA
≥97.0%
Form
Powder or crystals or crystalline powder
Loss on Drying
≤1.0%

Description

Thiamphenicol is used to treat chancroid in men and uncomplicated gonorrhea. It is used in studies of bacterial protein synthesis at the level of peptidyl transferase activity associated with the 23S rRNA of the 50S ribosomal subunit. It is used to study chloraniphenicol-thiamphenicol-resistance and the use of fluorinated analogs when resistance is encountered. Its main advantage over chloramphenicol is that it has never been associated with aplastic anaemia.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Thiamphenicol is used to treat chancroid in men and uncomplicated gonorrhea. It is used in studies of bacterial protein synthesis at the level of peptidyl transferase activity associated with the 23S rRNA of the 50S ribosomal subunit. It is used to study chloraniphenicol-thiamphenicol-resistance and the use of fluorinated analogs when resistance is encountered. Its main advantage over chloramphenicol is that it has never been associated with aplastic anaemia.

Solubility
Soluble in acetonitrile or DMF. Slightly soluble in water

Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
RUO – Research Use Only

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