2-Mercaptoethane sulfonic acid sodium salt is used as an adjuvant in cancer chemotherapy involving cyclophosphamide and ifosfamide. It is used as an antioxidant and cytoprotective agent in a wide variety of applications from protection from toxicity of therapeutic agents, such as cyclophosphamide to prevention from brain injury damage.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
2-Mercaptoethane sulfonic acid sodium salt is used as an adjuvant in cancer chemotherapy involving cyclophosphamide and ifosfamide. It is used as an antioxidant and cytoprotective agent in a wide variety of applications from protection from toxicity of therapeutic agents, such as cyclophosphamide to prevention from brain injury damage.
Solubility
Soluble in water. Also soluble in methanol, DMSO (33 mg/ml) and ethanol (<1mg/mL).
Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.
RUO – Research Use Only
General References:
- Ariela Marshall; Cindy McGrath; Drew Torigian; Nicholas Papanicolaou; Priti Lal; Carol Kaplan Tweed. Low-dose cyclophosphamide associated with hemorrhagic cystitis in a breast cancer patient. Breast Journal. 2012, 18,(3), 272-275.
- Nicole J.Look Hong; Francis J.Hornicek; David C.Harmon; Edwin Choy; Yen-Lin Chen; Sam S.Yoon; G.Petur Nielsen; Jackie Szymonifka; Beow Y.Yeap; Thomas F.DeLaney; John T.Mullen. Neoadjuvant chemoradiotherapy for patients with high-risk extremity and truncal sarcomas: A 10-year single institution retrospective study. European Journal of Cancer. 2013, 49,(4), 875-883.