Thermo Scientific Chemicals

5,6-Dichlorobenzimidazole riboside, 98%, Thermo Scientific Chemicals

Catalog number: J64870.MD
250 mg, Each
Thermo Scientific Chemicals

5,6-Dichlorobenzimidazole riboside, 98%, Thermo Scientific Chemicals

Catalog number: J64870.MD
250 mg, Each
Quantity
Catalog number: J64870.MD
also known as J64870-MD
Price (USD)
Price: 603.00
Online price: 512.65
Your price:
Quantity
-

Chemical Identifiers

CAS
53-85-0
IUPAC Name
(2R,3R,4S,5R)-2-(5,6-dichloro-1H-1,3-benzodiazol-1-yl)-5-(hydroxymethyl)oxolane-3,4-diol
Molecular Formula
C12H12Cl2N2O4
InChI Key
XHSQDZXAVJRBMX-DDHJBXDOSA-N
SMILES
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=CC(Cl)=C(Cl)C=C12
Appearance (Color)
White to pale cream
Form
Powder
Purity
≥97.5% (HPLC)

Description

Inhibits casein kinase II and blocks RNA synthesis. An adenosine analog.5,6-Dichlorobenzimidazole riboside is used as an inhibitor of RNA Polymerase II. It is nucleoside analogue and used in research to study the mechanisms of cellular regulation. Further, it inhibits some protein kinases.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Inhibits casein kinase II and blocks RNA synthesis. An adenosine analog.5,6-Dichlorobenzimidazole riboside is used as an inhibitor of RNA Polymerase II. It is nucleoside analogue and used in research to study the mechanisms of cellular regulation. Further, it inhibits some protein kinases.

Solubility
Soluble in DMSO to 75mMSoluble in dimethyl sulfoxide, hot ethanol, dimethyl formamide, (1:2) dimethyl formamide:Phosphate buffer saline, water, methanol and pyridine. Slightly soluble in aqueous buffers.

Notes
Incompatible with heat and oxidizing agents.
RUO – Research Use Only

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