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D-Mannosamine hydrochloride, 98%
Catalog number: J66316.03
1 g, Each
Thermo Scientific Chemicals
D-Mannosamine hydrochloride, 98%
Catalog number: J66316.03
1 g, Each
Quantity
Catalog number: J66316.03
also known as J66316-03
Price (USD)
207.65 Online price
243.00
Each
Quantity
-
Chemical Identifiers
CAS
5505-63-5
IUPAC Name
hydrogen (2S,3R,4S,5R)-2-amino-3,4,5,6-tetrahydroxyhexanoic acid chloride
Molecular Formula
C6H14ClNO6
InChI Key
JMVMHPCPPSZGNY-BZWNWTOPSA-N
SMILES
[H+].[Cl-].N[C@@H]([C@@H](O)[C@H](O)[C@H](O)CO)C(O)=O
Specifications
Specification SheetAppearance (Color)
White to off-white
Assay (HPLC)
97.5% min.
Residue on ignition
0.5% max.
Loss on Drying
0.5% max.
Form
Powder
Description
D-Mannosamine hydrochloride is used in the synthesis of non-natural Mannac analogs for the expression of thiols on cell-surface sialic acids. It is also used to investigate and screening of N-acetyl-beta-hexosaminidase inhibitor libraries targeting osteoarthritis. It acts as a precursor of N-propanoyl mannosamine and other N-acyl precursors of sialic acid (N-acyl neuraminic acids). It is a pharmaceutical compound used in the development of mannosylated liposomes for bioadhesive oral drug delivery through M cells of Peyer's patches.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
D-Mannosamine hydrochloride is used in the synthesis of non-natural Mannac analogs for the expression of thiols on cell-surface sialic acids. It is also used to investigate and screening of N-acetyl-beta-hexosaminidase inhibitor libraries targeting osteoarthritis. It acts as a precursor of N-propanoyl mannosamine and other N-acyl precursors of sialic acid (N-acyl neuraminic acids). It is a pharmaceutical compound used in the development of mannosylated liposomes for bioadhesive oral drug delivery through M cells of Peyer′s patches.
Solubility
Soluble in water and methanol.
Notes
Hygroscopic. Store in a cool place. Incompatible with strong oxidizing agents.
D-Mannosamine hydrochloride is used in the synthesis of non-natural Mannac analogs for the expression of thiols on cell-surface sialic acids. It is also used to investigate and screening of N-acetyl-beta-hexosaminidase inhibitor libraries targeting osteoarthritis. It acts as a precursor of N-propanoyl mannosamine and other N-acyl precursors of sialic acid (N-acyl neuraminic acids). It is a pharmaceutical compound used in the development of mannosylated liposomes for bioadhesive oral drug delivery through M cells of Peyer′s patches.
Solubility
Soluble in water and methanol.
Notes
Hygroscopic. Store in a cool place. Incompatible with strong oxidizing agents.
RUO – Research Use Only
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