Thermo Scientific Chemicals

Natamycin, 95%, Thermo Scientific Chemicals

Catalog number: J66468.MC
100 mg, Each
Thermo Scientific Chemicals

Natamycin, 95%, Thermo Scientific Chemicals

Catalog number: J66468.MC
100 mg, Each
Quantity
Informational:Informational:This chemical may require us to obtain additional information for our regulatory and chemical compliance records. If required, we will contact you for this information once your order is placed.
Catalog number: J66468.MC
also known as J66468-MC
Price (USD)
Price: 177.00
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Quantity
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Chemical Identifiers

CAS
7681-93-8
IUPAC Name
22-[(4-amino-3,5-dihydroxy-6-methyloxan-2-yl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-6,11,28-trioxatricyclo[22.3.1.0⁵,⁷]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid
Molecular Formula
C33H47NO13
InChI Key
NCXMLFZGDNKEPB-UHFFFAOYNA-N
SMILES
CC1OC(OC2CC3OC(O)(CC(O)C3C(O)=O)CC(O)CC3OC3C=CC(=O)OC(C)CC=CC=CC=CC=C2)C(O)C(N)C1O
Assay from Supplier's CofA
≥94.0% (HPLC)
Appearance (Color)
White to pale yellow to pale brown
Proton NMR
Conforms to structure
Form
Powder or crystals

Description

Pimaricin is an amphoteric antibiotic from Streptomyces chattanoogensis. It is used as an ergosterol and cholesterol binding agent to study lipid bilayer dynamics. It is used to study the pleitropic regulator AdpAch and the gamma-butyrolactone regulatory system of Streptomyces chattanoogensis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Natamycin is a member of the macrolide antibiotic class, compounds originally derived from Saccharopolyspora erythraea, a type of soil bacteria

• Natamycin is an amphoteric compound with both acid and basic properties

• Natamycin exhibits antifungal activity • Natamycin exerts its effects by binding sterols within fungal cell walls and increasing membrane permeability, leading to a loss of homeostasis within the cell

Application

• Natamycin is suitable for use in the laboratory study of fungal keratitis and other infections of fungal origin

• Natamycin may also be used in laboratory research of cell physiology and mechanisms of antibiotic resistance

RUO – Research Use Only

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