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Actinomycin D (1 mg/ml, DMSO)
Actinomycin D (1 mg/ml, DMSO)
Actinomycin D (1 mg/ml, DMSO)
Thermo Scientific Chemicals

Actinomycin D (1 mg/ml, DMSO)

CAS: 50-76-0 | C62H86N12O16 | 1255.438 g/mol
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1 mL
5 x 1 mL
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Catalog number J67160.8EQ
also known as J67160-8=
Price (EUR)
623,00
Each
Quantity:
5 x 1 mL
Request bulk or custom format
Price (EUR)
623,00
Each
Chemical Identifiers
CAS50-76-0
IUPAC Name2-amino-4,6-dimethyl-3-oxo-N1,N9-bis[2,5,9-trimethyl-1,4,7,11,14-pentaoxo-6,13-bis(propan-2-yl)-hexadecahydro-1H-pyrrolo[2,1-i]1-oxa-4,7,10,13-tetraazacyclohexadecan-10-yl]-3H-phenoxazine-1,9-dicarboxamide
Molecular FormulaC62H86N12O16
InChI KeyRJURFGZVJUQBHK-UHFFFAOYNA-N
SMILESCC(C)C1NC(=O)C(NC(=O)C2=C3N=C4C(OC3=C(C)C=C2)=C(C)C(=O)C(N)=C4C(=O)NC2C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C3CCCN3C(=O)C(NC2=O)C(C)C)C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C2CCCN2C1=O
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SpecificationsSpecification SheetSpecification Sheet
FormLiqiud
CommentActinomycin D: 1 mg/mL
Appearance (Color)Clear Yellow to Orange to Dark Orange-Red
Actinomycin D has a wide-ranging applications ranging from a selection agent in cell culture, use in studies of suppressing HIV-replication and programmed cell death of PC12 cells, and as an antibiotic in treatment of various malignant neoplasms, including Wilm?s tumor and the sarcomas.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Actinomycin D has a wide-ranging applications ranging from a selection agent in cell culture, use in studies of suppressing HIV-replication and programmed cell death of PC12 cells, and as an antibiotic in treatment of various malignant neoplasms, including Wilm′s tumor and the sarcomas.

Solubility
Soluble in acetonitrilie or acetone at 10 mg/mL and in DMSO at a minimum of 1 mg/mL, slightly soluble in water.

Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
RUO – Research Use Only

General References:

  1. Perry, R.P. Selective effects of actinomycin D on the intracellular distribution of RNA synthesis in tissue culture cells.Experimental Cell Research. 1963, 29, (3), 400-406.
  2. Paul R. Gross.; Gilles H. Cousineau. Effects of actinomycin D on macromolecule synthesis and early development in sea urchin eggs.Biochemical and Biophysical Research Communications. 1963, 10, (4), 321-326.