Thermo Scientific Chemicals

Chloroform, Molecular Biology Reagent

500 mL, Each
Thermo Scientific Chemicals

Chloroform, Molecular Biology Reagent

500 mL, Each
Quantity
Informational:Informational:This chemical may require us to obtain additional information for our regulatory and chemical compliance records. If required, we will contact you for this information once your order is placed.
Catalog number: J67241.AP
also known as J67241-AP
Price (USD)
Price: 82.90
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Quantity
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Chemical Identifiers

CAS
67-66-3
IUPAC Name
trichloromethane
Molecular Formula
CHCl3
InChI Key
HEDRZPFGACZZDS-UHFFFAOYSA-N
SMILES
ClC(Cl)Cl
Assay (special)
Lead (Pb): ≤0.00001% (≤0.1 ppm)
Appearance (Color)
Clear colorless
Assay (HPLC)
≥99.5%
Water Content (Karl Fischer Titration)
≤0.02%
Form
Liquid

Description

Chloroform is a common laboratory reagent favored for use as a solvent due to the compounds relative unreactivity and miscibility with most organic compounds. Chloroform is also used in organic synthesis as a source for CCl2. In the swine tracheal smooth muscle, chloroform has been demonstrated to directly and in a concentration dependent manner induce contractions. It has been observed that Chloroform can release Ca2+ from ryanodine sensitive receptors in chloroform-induced contraction in swine tracheal smooth muscle. At concentrations of 100 and 250 ppm in mouse splenocyte, basal proliferation was increased yet a decrease in circulating neutrophils was documented.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Chloroform is a common laboratory reagent favored for use as a solvent due to the compounds relative unreactivity and miscibility with most organic compounds. Chloroform is also used in organic synthesis as a source for CCl2. In the swine tracheal smooth muscle, chloroform has been demonstrated to directly and in a concentration dependent manner induce contractions. It has been observed that Chloroform can release Ca2+ from ryanodine sensitive receptors in chloroform-induced contraction in swine tracheal smooth muscle. At concentrations of 100 and 250 ppm in mouse splenocyte, basal proliferation was increased yet a decrease in circulating neutrophils was documented.

Solubility
Soluble in water at 20°C 8 g/L.

Notes
Stabilized with approx. 50 ppm amylene
WARNING: Cancer and Reproductive Harm – www.P65Warnings.ca.gov
RUO – Research Use Only