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Kanamycin, 50 mg/ml in distilled water, sterile-filtered
Catalog number: J67354.AE
100 mL, Each
Thermo Scientific Chemicals
Kanamycin, 50 mg/ml in distilled water, sterile-filtered
Catalog number: J67354.AE
100 mL, Each
Quantity
Catalog number: J67354.AE
also known as J67354-AE
Price (USD)
Price: 347.00
Online price: 294.65
Your price:
Quantity
-
Chemical Identifiers
CAS
25389-94-0
IUPAC Name
(2R,3S,4S,5R,6R)-2-(aminomethyl)-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-3-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}oxane-3,4,5-triol; sulfuric acid
Molecular Formula
C18H38N4O15S
InChI Key
OOYGSFOGFJDDHP-KMCOLRRFSA-N
SMILES
OS(O)(=O)=O.NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O
Specifications
Specification SheetForm
Liquid
Appearance (Color)
Clear colorless
Comment
50mg/ml aqueous solution is prepared in 18 megohm-cm ñ 1 water. The solution is filter sterilized using 0.22 micron filter
Description
It has been used in tissue culture media. It is used as an additive in culture media for the isolation of group D streptococci on Kanamycin Esculin Azide Agar and for selection of transformed plant cells containing the neomycin phosphotransferase on a kanamycin-medium. It can also be used as a selection agent for cells transformed with kanamycin B resistance gene. It is recommended for use in cell culture applications at 100mg/mL. Kanamycin can be used as a selection agent in several types of isolation media.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Kanamycin monosulfate is the sulfate salt form of kanamycin A
• It was isolated from Streptomyces kanamyceticus
• This compound inhibits translocation during protein biosynthesis. It binds to the 30S ribosomal subunit, causing misreading of the mRNA sequence
Application
• Kanamycin monosulfate shows antibacterial activity. It is effective against gram-positive and gram-negative bacteria, as well as Mycoplasma species
• This compound is also involved in translating prokaryotic ribosomes
• In molecular biology experiments, it is commonly used to select and isolate transformants expressing the kanamycin resistance gene, and plants that have the NPT II (APH3) gene incorporated
RUO – Research Use Only
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