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GeneBLAzer® CALCRL:RAMP3-CRE-bla FreeStyle™ 293F Cells

Catalog number: K1439

 Related applications: Target & Lead Identification & Validation

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Description

The GeneBLAzer® CALCRL:RAMP3-CRE-bla FreeStyle™ 293F cells contain the human Amylin Receptor 2 (CALCRL:RAMP3), (Accession # NM_005795.3 NM_005856.1) stably integrated into the CellSensor® CRE-bla Freestyle™ 293F cell line. CellSensor® CRE-bla Freestyle™ 293F cells (Cat # K1130) contain a beta-lactamase (bla) reporter gene under control of the cAMP response element (CRE).

CALCRL:RAMP3-CRE-bla FreeStyle™ 293F cells are functionally validated for Z'-factor and EC50 concentrations of Adrenomedullin(1-52). In addition, CALCRL:RAMP3-CRE-bla FreeStyle™ 293F cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary in the Manuals and Brochures section.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

System: GeneBLAzer®
Reporter: BLA (Beta-Lactamase)
Cell Line: FreeStyle™ 293-F Cells
Cell State: Dividing Cells
Gene Symbol: CALCRL:RAMP3
Product Size: 8 x 106 cells
Accession Number: NM_005855.2
Detection Method: Fluorescent
Druggable Target: GPCRs
Population Status: Single Cell Clone Origin

Contents & storage

(LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
Includes:
• GeneBLAzer® CALCRL:RAMP3-CRE-bla Freestyle™ 293F cells
• GeneBLAzer® CALCRL:RAMP3-CRE-bla Freestyle™ 293F Assay Protocol
• Certificate of Analysis
The GeneBLAzer® CALCRL:RAMP3-CRE-bla Freestyle™ 293F cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

Documents

Manuals & protocols

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