The GeneBLAzer™ CALCRL:RAMP3-CRE-bla FreeStyle™ 293F cells contain the human Amylin Receptor 2 (CALCRL:RAMP3), (Accession # NM_005795.3 NM_005856.1) stably integrated into the CellSensor™ CRE-bla Freestyle™ 293F cell line. CellSensor™ CRE-bla Freestyle™ 293F cells (Cat # K1130) contain a beta-lactamase (bla) reporter gene under control of the cAMP response element (CRE).
CALCRL:RAMP3-CRE-bla FreeStyle™ 293F cells are functionally validated for Z'-factor and EC50 concentrations of Adrenomedullin(1-52). In addition, CALCRL:RAMP3-CRE-bla FreeStyle™ 293F cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary in the Manuals and Brochures section.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession Number
NM_005855.2
Assay Entry
Cell-based beta lactamase reporter gene
Cell State
Dividing Cells
Detection Method
Fluorescent
Gene Symbol
CALCRL:RAMP3
Population Status
Single Cell Clone Origin
Product Line
Freestyle™, GeneBLAzer™
Reporter Gene
BLA (Beta-Lactamase)
Target Entry
CALCRL:RAMP3
Cell Line
FreeStyle 293-F Cells
System Type
GeneBLAzer™
Druggable Target
GPCR
Contents & Storage
(LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol). Includes: • GeneBLAzer™ CALCRL:RAMP3-CRE-bla Freestyle™ 293F cells • GeneBLAzer™ CALCRL:RAMP3-CRE-bla Freestyle™ 293F Assay Protocol • Certificate of Analysis The GeneBLAzer™ CALCRL:RAMP3-CRE-bla Freestyle™ 293F cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.