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Thermo Scientific™

Tango™ ADORA1-bla U2OS Cells

Catalog number: K1445
Thermo Scientific™

Tango™ ADORA1-bla U2OS Cells

Catalog number: K1445
Catalog Number
K1445
Unit Size
2 x 106 cells
Price (USD)
8,140.00
Your Price:
Availability
***
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
K14452 x 106 cells
8,140.00
Your Price:
***
Product Overview
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The Tango™ ADORA1-bla U2OS cells contain the human Adenosine A1 receptor (ADORA1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element.

The Tango™ ADORA1-bla U2OS cells have been functionally validated for Z' factor and EC50 concentrations of NECA. In addition, Tango™ ADORA1-bla U2OS cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary in the Manuals and Brochures section.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number
NM_000674.1
Assay Entry
Cell-based beta-arrestin recruitment
Cell State
Dividing Cells
Cytoplasmic Tail
Tail from AVPR2 GPCR
Detection Method
Fluorescent
Gene Symbol
ADORA1A
Population Status
Pool of Stable Cells
Product Line
Tango™
Reporter Gene
BLA (Beta-Lactamase)
Target Entry
ADORA1
Cell Line
U2OS
System Type
Tango™
Druggable Target
GPCRs

Contents & Storage

(LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
Includes:
o Tango™ ADORA1-bla U2OS cells
o Tango™ ADORA1-bla U2OS Assay Protocol
o Certificate of Analysis
The Tango™ ADORA1-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

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