The GeneBLAzer™ ADRA1B-NFAT-bla CHO-K1 cells contain the human Complement Component 5a Receptor 1 (ADRA1B) stably integrated into the GeneBLAzer™ NFAT-bla CHO-K1 cell line. GeneBLAzer™ NFAT-bla CHO-K1 (Cat # K1447) contains a beta-lactamase (bla) reporter gene under control of a NFAT response element stably integrated into CHO-K1 cells.
The ADRA1B-NFAT-bla CHO-K1 cells are functionally validated for Z'-factor and EC50 concentrations using established ligands. In addition, ADRA1B-NFAT-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession Number
NM_000679.3
Assay Entry
Cell-based beta lactamase reporter gene
Cell State
Dividing Cells
Detection Method
Fluorescent
Gene Symbol
ADRA1B
Population Status
Pool of Stable Cells
Product Line
GeneBLAzer™
Reporter Gene
BLA (Beta-Lactamase)
Target Entry
ADRA1B
Type
CHO-K1 Cells
Cell Line
CHO-K1
System Type
GeneBLAzer™
Druggable Target
GPCR
Contents & Storage
K1471 GeneBLAzer™ ADRA1B-NFAT-bla CHO-K1 cells (LiveBLAzer™-FRET B⁄G Loading Kit, Solution D and other materials are required separately; please refer to the protocol). Includes: • GeneBLAzer™ ADRA1B-NFAT-bla CHO-K1 cells • GeneBLAzer™ ADRA1B-NFAT-bla CHO-K1 Assay Protocol • Certificate of Analysis
Storage: The GeneBLAzer™ ADRA1B-NFAT-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.