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GeneBLAzer™ MC2R-CRE-bla-CHO-K1 Cells

Catalog number:  K1483

Related applications:

Pharma & Biopharma

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Description

The GeneBLAzer® MC2R-CRE-bla-CHO-K1 cells contain the human melanocortin-2 receptor (MC2R), (Accession # NM_000529.1) and the Melanocortin-2 receptor accessory protein (MRAP), (Accession #NM_178817.3) stably integrated into the CellSensor® CRE-bla CHO-K1 cell line. CellSensor® CRE-bla CHO-K1 cells (Cat # K1129) contain a beta-lactamase (bla) reporter gene under control of the cAMP Response Element (CRE).

The MC2R-CRE-bla-CHOK1 cells are functionally validated for Z'-factor and EC50 concentrations of ACTH 1-24. In addition, MC2R-CRE-bla-CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary in the Manuals and Brochures section.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NM_000529.2
Assay Entry: Cell-based beta lactamase reporter gene
Cell Line: CHO-K1
Cell State: Dividing Cells
Detection Method: Fluorescent
Druggable Target: GPCRs
Gene Symbol: MC2R
Population Status: Single Cell Clone Origin
Product Line: GeneBLAzer®
Reporter Gene: BLA (Beta-Lactamase)
System Type: GeneBLAzer™
Target Entry: MC2R

Contents & storage

(LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
Includes:
o GeneBLAzer ® MC2R-CRE-bla-CHO-K1 cells
o GeneBLAzer ® MC2R-CRE -bla CHO-K1 Assay Protocol
o Certificate of Analysis
The GeneBLAzer® MC2R-CRE -bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.