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Tango™ DRD1-bla U2OS Cells

Catalog number: K1485

 Related applications: Target & Lead Identification & Validation

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Description

The Tango™ DRD1-bla U2OS cells contain the human Dopamine Receptor 1 (DRD1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element.

The Tango™ DRD1-bla U2OS cell line has been functionally validated for Z'-factor and EC50 concentrations of dihydrexidine. The DRD1 cells have been tested for assay performance under variable assay conditions. These data are available in the Validation & Assay Performance Summary in the Manuals and Brochures section.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Color: Assorted Colors, Optical
Format: 384-well plate
Barcode: Includes Barcode
Product Size: 5 plates
Reaction Speed: Standard
For Use With (Equipment): 7900HT System, Veriti® Dx Thermal Cycler, QuantStudio™ Dx, QuantStudio™, 3130 Genetic Analyzer, 3130xl Genetic Analyzer, ViiA™ 7 Dx System, 3500xL Dx Genetic Analyzer, 3730xl DNA Analyzer, 3500 Dx Genetic Analyzer, Veriti® Thermal Cycler, 3500xL Genetic Analyzer, 3730 DNA Analyzer, ViiA™ 7 System, 3500 Genetic Analyzer, GeneAmp™ 9700

Contents & storage

(LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
Includes:
o Tango™ DRD1-bla U2OS cells
o Tango™ DRD1-bla U2OS Assay Protocol
o Certificate of Analysis
The Tango™ DRD1-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

Documents

Manuals & protocols