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Thermo Scientific™

GeneBLAzer™ T-Rex™ GPR119-CRE-bla CHO-K1 Cells

Catalog number:  K1486

Related applications:

Pharma & Biopharma

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Description

The GeneBLAzer® T-Rex™ GPR119-CRE-bla CHO-K1 cells contain the human G-Protein Receptor 119 (GPR119), (Accession # NP_848566) stably integrated into the CellSensor® CRE-bla CHO-K1 cell line. CellSensor® CRE-bla CHO-K1 cells (Cat # K1129) contain a beta-lactamase (bla) reporter gene under control of the cAMP response element.

The T-Rex™ GPR119-CRE-bla CHO-K1 cells are functionally validated for Z'-factor and EC50 concentrations of AR231453(1). In addition, T-Rex™ GPR119-CRE-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary in the Manuals and Brochures section.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NM_178471.1
Assay Entry: Cell-based beta lactamase reporter gene
Cell Line: CHO-K1
Cell State: Dividing Cells
Detection Method: Fluorescent
Druggable Target: GPCRs
Gene Symbol: GPR119
Population Status: Single Cell Clone Origin
Product Line: GeneBLAzer®
Reporter Gene: BLA (Beta-Lactamase)
Shipping Condition: Room Temperature
System Type: GeneBLAzer™
Target Entry: GPR119

Contents & storage

(LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
Includes:
o GeneBLAzer® T-Rex™ GPR119-CRE-bla CHO-K1 cells
o GeneBLAzer® T-Rex™ GPR119-CRE-bla CHO-K1 Assay Protocol
o Certificate of Analysis
The GeneBLAzer® T-Rex™ GPR119-CRE-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.