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GeneBLAzer® FPRL-1-Gα15-NFAT-bla CHO-K1 Cells

Catalog number: K1532

 Related applications: Target & Lead Identification & Validation

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Description

GeneBLAzer® FPRL-1-Gα15-NFAT-bla CHO-K1 cells contain the human Formyl Peptide Like Receptor 1 (FPRL-1) stably integrated into the GeneBLAzer® Gα15-NFAT-bla CHO-K1 cell line. GeneBLAzer® Gα15-NFAT-bla CHO-K1 cells (Cat. no. K1537) contain a beta-lactamase reporter gene under control of the Nuclear Factor of Activated T-cells (NFAT) response element and the Promiscuous G protein, Gα15.

The GeneBLAzer® FPRL-1-Gα15-NFAT-bla CHO-K1 cells are functionally validated for Z' and EC50 concentrations of W Peptide. In addition, GeneBLAzer® FPRL-1-Gα15-NFAT-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

The FPRL-1 receptor has been implicated in a variety of inflammation and neurological disorders, including Alzheimer's disease.

For Academic pricing please login or contact us at discoverysciences@invitrogen.com.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

System: GeneBLAzer®
Reporter: BLA (Beta-Lactamase)
Cell Line: CHO-K1
Technique: FRET
Cell State: Dividing Cells
Gene Symbol: FPRL-1
Product Size: 2 x 106 cells
Accession Number: NM_001462
Detection Method: Fluorescent
Druggable Target: GPCRs
Population Status: Single Cell Clone Origin

Contents & storage

Contents:
K1532 GeneBLAzer® FPRL-1-Gα15-NFAT-bla CHO-K1 cells
(LiveBLAzer™-FRET B⁄G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
Includes:
• GeneBLAzer® FPRL-1-Gα15-NFAT-bla CHO-K1 cells
• GeneBLAzer® FPRL-1-Gα15-NFAT-bla CHO-K1 Assay Protocol
• Certificate of Analysis

Storage:
The GeneBLAzer® FPRL-1-Gα15-NFAT-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

Documents

Manuals & protocols