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Catalog Number
K1562
Unit Size
8 x 106 cells
Price (USD)
Price: 9,950.00
Your Price:
Availability
-
Quantity
| Catalog Number | Unit Size | Price (USD) | Availability | Quantity | |
|---|---|---|---|---|---|
| K1562 | 8 x 106 cells | Price: 9,950.00 Your Price: | - |
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The Tango™ HTR2A-bla U2OS cells contain the human Serotonin Type 2A receptor (HTR2A) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin⁄TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element.
The Tango™ HTR2A-bla U2OS cells have been functionally validated for Z' factor and EC50 concentrations of established ligands. In addition, Tango™ HTR2A-bla U2OS cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary for each product.
The Tango™ HTR2A-bla U2OS cells have been functionally validated for Z' factor and EC50 concentrations of established ligands. In addition, Tango™ HTR2A-bla U2OS cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary for each product.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession Number
NM_000621.2
Assay Entry
Cell-based beta-arrestin recruitment
Cell State
Dividing Cells
Cytoplasmic Tail
Tail from AVPR2 GPCR
Detection Method
Fluorescent
Gene Symbol
HTR2A
Population Status
Single Cell Clone Origin
Product Line
GeneBLAzer™
Protein Family
GPCR (G-Protein Coupled Receptors)
Readout
End Point
Reporter Gene
BLA (Beta-Lactamase)
Target Entry
HTR2A
Cell Line
U2OS
System Type
Tango™
Druggable Target
GPCRs
Contents & Storage
K1562 Tango™HTR2A-bla U2OS cells
(LiveBLAzer™-FRET B⁄G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
Includes:
• Tango™ HTR2A-bla U2OS cells
• Tango™ HTR2A-bla U2OS Assay Protocol
• Certificate of Analysis
The Tango™ HTR2A-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
(LiveBLAzer™-FRET B⁄G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
Includes:
• Tango™ HTR2A-bla U2OS cells
• Tango™ HTR2A-bla U2OS Assay Protocol
• Certificate of Analysis
The Tango™ HTR2A-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
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