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Tango™ OPRK1-bla U2OS Cells

Catalog number: K1576

Tango™ OPRK1-bla U2OS Cells

Catalog number: K1576
Catalog Number
K1576
Unit Size
2 x 106 cells
Price (USD)
7,920.00
Your Price:
Availability
***
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
K15762 x 106 cells
7,920.00
Your Price:
***
Product Overview
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The Tango™ OPRK1-bla U2OS cells contain the human Opiod Receptor Kappa 1 (OPRK1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin⁄TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element.

The Tango™ OPRK1-bla U2OS cells cells have been functionally validated for Z' factor and EC50 concentrations of established ligands. In addition, Tango™ OPRK1-bla U2OS cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary for each product.

Specifications

Accession Number
NM_000912
Assay Entry
Cell-based beta-arrestin recruitment
Cell State
Dividing Cells
Cytoplasmic Tail
Tail from AVPR2 GPCR
Detection Method
Fluorescent
Gene Symbol
OPRK1
Population Status
Pool of Stable Cells
Product Line
Tango™
Reporter Gene
BLA (Beta-Lactamase)
Target Entry
OPRK1
Cell Line
U2OS
System Type
Tango™
Druggable Target
GPCRs

Contents & Storage

K1576 Tango™ OPRK1-bla U2OS cells
(LiveBLAzer™-FRET B⁄G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
Includes:
• Tango™ OPRK1-bla U2OS cells
• Tango™ OPRK1-bla U2OS Assay Protocol
• Certificate of Analysis

Storage:
The Tango™ OPRK1-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

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