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Tango™ ADRA2A-bla U2OS Cells

Catalog number: K1604

 Related applications: Pharma & Biopharma | Target & Lead Identification & Validation

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The Tango™ ADRA2A-bla U2OS cells contain the human Adrenergic, Alpha-2A-, Receptor (ADRA2A) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin⁄TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element.

The Tango™ ADRA2A-bla U2OS cells cells have been functionally validated for Z' factor and EC50 concentrations of established ligands. In addition, Tango™ ADRA2A-bla U2OS cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary for each product.
For Research Use Only. Not for use in diagnostic procedures.


System: Tango™
Reporter: BLA (Beta-Lactamase)
Cell Line: U2OS
Cell State: Dividing Cells
Gene Symbol: ADRA2A
Product Size: 2 x 106 cells
Accession Number: NM_000681.2
Cytoplasmic Tail: Tail from AVPR2 GPCR
Detection Method: Fluorescent
Druggable Target: GPCRs
Population Status: Single Cell Clone Origin

Contents & storage

K1604 Tango™ ADRA2A-bla U2OS cells
(LiveBLAzer™-FRET B⁄G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
• Tango™ ADRA2A-bla U2OS cells
• Tango™ ADRA2A-bla U2OS Assay Protocol
• Certificate of Analysis

The Tango™ ADRA2A-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.


Manuals & protocols