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The CellSensor® IL-1-bla ECV304 cell line is an adherent human urinary bladder cell line used to measure the (IL-1) signaling pathway via transcriptional regulation of the beta-lactamase gene. IL-1 cytokine cell signaling is a critical pathway involved in immune and inflammatory responses. This cell line was constructed using GenomeScreen™ technology utilizing a promoterless beta-lactamase reporter gene randomly integrated into the genome of the IL-1-bla ECV304 cell line. Sequential rounds of sorting were performed to isolate cell clones containing tagged genes induced by IL-1. A dose response assay was run with this cell line using IL-1 as the agonist. Academic and non-profit customers, please inquire for special pricing.
For Research Use Only. Not for use in diagnostic procedures.
Cell-based beta lactamase reporter gene
Cytokines, Signaling Pathway
Interleukin 1 pathway, IRAK
Contents & storage
CellSensor® Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.