CellSensor™ ISRE-bla HEK293T Cell Line
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Thermo Scientific™

CellSensor™ ISRE-bla HEK293T Cell Line

Interferon cell signaling is a critical pathway involved in viral defense and autoimmune disease. The CellSensor™ ISRE-bla HEK 293T cellRead more
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Catalog number K1655
Price (USD)/ Each
10,930.00
-
Add to cart
Price (USD)/ Each
10,930.00
Add to cart
CellSensor™ ISRE-bla HEK293T Cell Line
Catalog numberK1655
Price (USD)/ Each
10,930.00
-
Add to cart

Interferon cell signaling is a critical pathway involved in viral defense and autoimmune disease. The CellSensor™ ISRE-bla HEK 293T cell line is responsive to interferon alpha and can be used to probe the JAK/STAT signaling pathway. The CellSensor™ ISRE-bla HEK 293T cell line contains the β-lactamase reporter gene under the control of the interferon stimulated response element (ISRE). This cell line was engineered by transduction of the ISRE-bla construct into HEK 293T cells by lentivirus. Flow cytometry was then used to isolate a pool of clones responsive to interferon alpha a stimulation. A dose response curve for this assay against interferon alpha is available in the validation packet. Academic and non-profit customers, please inquire for special pricing.

For Research Use Only. Not for use in diagnostic procedures.
Specifications
Assay EntryCell-based beta lactamase reporter gene
Cell StateDividing Cells
Product LineCellSensor™
Quantity1 Vial
Target EntryJAK/STAT (Type I IFN) pathway, TYK2, JAK1
System TypeCellSensor™
Druggable TargetSignaling Pathway
Unit SizeEach
Contents & Storage
CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.