Invitrogen™

CellSensor™ NFKB-bla HEK293T Cell Line

Catalog number: K1664
Invitrogen™

CellSensor™ NFKB-bla HEK293T Cell Line

Catalog number: K1664
Catalog Number
K1664
Unit Size
1 vial
Price (USD)
Price: 9,190.00
Your Price:
Availability
-
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
K16641 vial
Price: 9,190.00
Your Price:
-
Product Overview
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The CellSensor® NFκB-bla HEK 293T cell line contains a beta-lactamase reporter gene under the control of the Nuclear Factor kappa B (NFκB) response element. To obtain the cell line, the NFκB-bla construct was transduced into HEK 293T cells by lentivirus. Subsequent flow cytometry was used to isolate clones responsive to Tumor Necrosis Factor alpha (TNFα). The cell line has been validated for DMSO tolerance, stimulation time, substrate loading time, and EC50 concentration of TNF&alpha. This cell line is responsive to TNFα and can be used to probe NFκB signaling pathways, including those that are involved in apoptosis, viral defense, cancer, inflammation, and autoimmune disease. Academic and non-profit customers, please inquire for special pricing.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Assay Entry
Cell-based beta lactamase reporter gene
Cell State
Dividing Cells
Product Line
CellSensor™
Target Entry
TNF alpha, NIK, TLR, I kappa B, IRAK, IKK, NF-kappa B pathway
System Type
CellSensor™
Druggable Target
Signaling Pathway

Contents & Storage

CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.