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Thermo Scientific™

Tango™ MTNR1A-bla U2OS Cells

Catalog number: K1669
Thermo Scientific™

Tango™ MTNR1A-bla U2OS Cells

Catalog number: K1669
Catalog Number
K1669
Unit Size
8 x 106 cells
Price (USD)
Catalog NumberUnit SizePrice (USD)
K16698 x 106 cellsContact Us ›
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The Tango™ MTNR1A-bla U2OS cells contain the human Melatonin Receptor 1A (MTNR1A) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element.

The Tango™ MTNR1A-bla U2OS cells have been functionally validated for Z' factor and EC50 concentrations of established ligands. In addition, Tango™ MTNR1A-bla U2OS cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary for each product.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number
NM_005958.3
Assay Entry
Cell-based beta-arrestin recruitment
Cell State
Dividing Cells
Cytoplasmic Tail
Native Tail
Detection Method
Fluorescent
Gene Symbol
MTNR1A
Population Status
Single Cell Clone Origin
Product Line
GeneBLAzer™
Protein Family
GPCR (G-Protein Coupled Receptors)
Readout
End Point
Reporter Gene
BLA (Beta-Lactamase)
Target Entry
MTNR1A
Cell Line
U2OS
System Type
Tango™
Druggable Target
GPCRs

Contents & Storage

K1669 Tango™ MTNR1A-bla U2OS cells
(LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
Includes:
• Tango™ MTNR1A-bla U2OS cells
• Tango™ MTNR1A-bla U2OS Assay Protocol
• Certificate of Analysis
The Tango™ MTNR1A-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

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