GeneBLAzer™ HTR7 CHO-K1 DA (Division Arrested) cells and HTR7-CRE-bla CHO-K1 cells contain the human 5-hydroxytryptamine (serotonin) receptor 7 (Accession# NM_019860.2) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line. CellSensor™ CRE-bla CHO-K1 cells (Cat. no. K1535) contain a beta-lactamase (bla) reporter gene under control of the Cyclic AMP Response Element (CRE).
GeneBLAzer™ HTR7-CRE-bla CHO-K1 cells are functionally validated for Z'-factor and EC50 concentrations of 5-hydroxytryptamine (5-HT). In addition, GeneBLAzer™ HTR7-CRE-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.
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For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession Number
NM_019860.2
Assay Entry
Cell-based beta lactamase reporter gene
Cell State
Dividing Cells
Detection Method
Fluorescent
For Use With (Application)
FRET
Gene Symbol
HTR7
Population Status
Single Cell Clone Origin
Product Line
GeneBLAzer™
Reporter Gene
BLA (Beta-Lactamase)
Target Entry
HTR7
Cell Line
CHO-K1
System Type
GeneBLAzer™
Druggable Target
GPCRs
Contents & Storage
Contents: K1704 GeneBLAzer™ HTR7-CRE-bla CHO-K1 cells (LiveBLAzer™-FRET B⁄G Loading Kit, Solution D and other materials are required separately; please refer to the protocol). Includes: • GeneBLAzer™ HTR7-CRE-bla CHO-K1 cells • GeneBLAzer™ HTR7-CRE-bla CHO-K1 Assay Protocol • Certificate of Analysis
Storage: The GeneBLAzer™ HTR7-CRE-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.