|Catalog Number||Unit Size||Price (USD)||Availability||Quantity|
|K1706||2 × 10^6 cells|
GeneBLAzer™ VPAC2-CRE-bla CHO-K1 cells contain the human Vasoactive intestinal peptide/pituitary adenylate cyclase activating polypeptide receptor 2 (VPAC2) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line. CellSensor™ CRE-bla CHO-K1 cells (Cat. no. K1535) contain a beta-lactamase reporter gene under control of the Cyclic AMP Response Element (CRE) response element.
The GeneBLAzer™ VPAC2-CRE-bla CHO-K1 cells are functionally validated for Z' and EC50 concentrations of VIP. In addition, GeneBLAzer™ VPAC2-CRE-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.
VPAC2 has been implicated in a wide range of autoimmune and inflammation disorders, including Chronic obstructive pulmonary disease, Chronic Fatigue Syndrome. VPAC2 may also play a role in Type-2 diabetes.