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Thermo Scientific™

GeneBLAzer™ D2-Gqo5-NFAT-bla CHO-K1 Cells

Catalog number: K1708
Thermo Scientific™

GeneBLAzer™ D2-Gqo5-NFAT-bla CHO-K1 Cells

Catalog number: K1708
Catalog Number
K1708
Unit Size
2 x 106 cells
Price (USD)
8,140.00
Your Price:
Availability
***
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
K17082 x 106 cells
8,140.00
Your Price:
***
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GeneBLAzer® D2-Gqo5-NFAT-bla CHO-K1 cells contain the human Dopamine Receptor 2 (D2) stably integrated into the GeneBLAzer® Gqo5-NFAT-bla CHO-K1 cell line. GeneBLAzer® Gqo5-NFAT-bla CHO-K1 cells (K1536) contain a beta-lactamase reporter gene under control of the Nuclear Factor of Activated T-cells (NFAT) response element and the Chimeric G protein, Gqo5.

The GeneBLAzer® D2-Gqo5-NFAT-bla CHO-K1 cells are functionally validated for Z' and EC50 concentrations of apomorphine. In addition, GeneBLAzer® D2-Gqo5-NFAT-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

The D2 receptor is found primarily in the brain. There are two forms of D2 which are created by alternate splicing: a short form and a long form. This assay uses the long form, although little difference in ligand binding or signaling has been seen between the two forms.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number
NM_000795
Assay Entry
Cell-based beta lactamase reporter gene
Cell State
Dividing Cells
Detection Method
Fluorescent
For Use With (Application)
FRET
Gene Symbol
D2
Population Status
Single Cell Clone Origin
Product Line
GeneBLAzer™
Reporter Gene
BLA (Beta-Lactamase)
Target Entry
DRD2, D2
Cell Line
CHO-K1
System Type
GeneBLAzer™
Druggable Target
GPCRs

Contents & Storage

• GeneBLAzer™ D2-Gqo5-NFAT-bla CHO-K1 cells
• GeneBLAzer™ D2-Gqo5-NFAT-bla CHO-K1 Assay Protocol
• Certificate of Analysis

The GeneBLAzer™ D2-Gqo5-NFAT-bla CHO-K1 cells should be stored in liquid nitrogen immediately upon receipt.

LiveBLAzer™-FRET B/G Loading Kit, Solution D, and other materials are required separately; please refer to the protocol.

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