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      GeneBLAzer™ AVPR2-CRE-bla CHO-K1 Cells

      Catalog number:  K1718

       Related applications: Pharma & Biopharma | Target & Lead Identification & Validation

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      Description

      GeneBLAzer® AVPR2 CRE-bla CHO-K1 cells contain the human Arginine Vasopressin 2 (AVPR2) receptor stably integrated into the CellSensor® CRE-bla CHO-K1 cell line. CellSensor® CRE-bla CHO-K1 cells (Cat. no. K1535) contain a beta-lactamase reporter gene under control of the Cyclic AMP Response Element (CRE) response element.

      The GeneBLAzer® AVPR2 CRE-bla CHO-K1 cells are functionally validated for Z' and EC50 concentrations of dDAVP. In addition, GeneBLAzer® AVPR2 CRE-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

      Agonists and antagonists of the AVPR2 receptors are in various stages of clinical trials for the treatment of hypertension and as diuretics.

      For Academic pricing please login or contact us at discoverysciences@invitrogen.com.
      For Research Use Only. Not for use in diagnostic procedures.

      Specifications

      Gene Symbol: AVPR2
      Accession Number: NM_000054
      Cell Line: CHO-K1
      Cell State: Dividing Cells
      Detection Method: Fluorescent
      Druggable Target: GPCRs
      Population Status: Single Cell Clone Origin
      Product Line: GeneBLAzer®
      Product Size: 2 x 106 cells
      Reporter: BLA (Beta-Lactamase)
      System: GeneBLAzer™
      Technique: FRET

      Contents & storage

      Contents:
      K1718 GeneBLAzer® AVPR2 CRE-bla CHO-K1 cells
      (LiveBLAzer™-FRET B⁄G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
      Includes:
      • GeneBLAzer® AVPR2 CRE-bla CHO-K1 cells
      • GeneBLAzer® AVPR2 CRE-bla CHO-K1 Assay Protocol
      • Certificate of Analysis

      Storage:
      The GeneBLAzer® AVPR2 CRE-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

      Documents

      Manuals & protocols