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GeneBLAzer™ AVPR2-CRE-bla CHO-K1 Cells

Catalog number:  K1718

Related applications:

Pharma & Biopharma

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Description

GeneBLAzer® AVPR2 CRE-bla CHO-K1 cells contain the human Arginine Vasopressin 2 (AVPR2) receptor stably integrated into the CellSensor® CRE-bla CHO-K1 cell line. CellSensor® CRE-bla CHO-K1 cells (Cat. no. K1535) contain a beta-lactamase reporter gene under control of the Cyclic AMP Response Element (CRE) response element.

The GeneBLAzer® AVPR2 CRE-bla CHO-K1 cells are functionally validated for Z' and EC50 concentrations of dDAVP. In addition, GeneBLAzer® AVPR2 CRE-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

Agonists and antagonists of the AVPR2 receptors are in various stages of clinical trials for the treatment of hypertension and as diuretics.

For Academic pricing please login or contact us at discoverysciences@invitrogen.com.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NM_000054
Assay Entry: Cell-based beta lactamase reporter gene
Cell Line: CHO-K1
Cell State: Dividing Cells
Druggable Target: GPCRs
Gene Symbol: AVPR2
Population Status: Single Cell Clone Origin
Product Line: GeneBLAzer®
Reporter Gene: BLA (Beta-Lactamase)
System Type: GeneBLAzer™
Target Entry: AVPR2
Technique: FRET
Detection Method: Fluorescent

Contents & storage

Contents:
K1718 GeneBLAzer® AVPR2 CRE-bla CHO-K1 cells
(LiveBLAzer™-FRET B⁄G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
Includes:
• GeneBLAzer® AVPR2 CRE-bla CHO-K1 cells
• GeneBLAzer® AVPR2 CRE-bla CHO-K1 Assay Protocol
• Certificate of Analysis

Storage:
The GeneBLAzer® AVPR2 CRE-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.