GeneBLAzer™ GPR54-NFAT-bla CHO-K1 cells contain the human KiSS1 receptor (GPR54) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line. CellSensor™ NFAT-bla CHO-K1 cells (Cat. no. K1534) contain a beta-lactamase reporter gene under control of the Nuclear Factor of Activated T-cells (NFAT) response element.
The GeneBLAzer™ GPR54-NFAT-bla CHO-K1 cells are functionally validated for Z' and EC50 concentrations of Metastin. In addition, GeneBLAzer™ GPR54-NFAT-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.
The GPR54 receptor has been shown to be involved in tumor progression and metastasis, and in the development and functional regulation of the gonads.
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For Research Use Only. Not for use in diagnostic procedures.
Cell-based beta lactamase reporter gene
For Use With (Application)
Single Cell Clone Origin
Contents & Storage
Contents: K1720 GeneBLAzer™ GPR54-NFAT-bla CHO-K1 cells (LiveBLAzer™-FRET B⁄G Loading Kit, Solution D and other materials are required separately; please refer to the protocol). Includes: • GeneBLAzer™ GPR54-NFAT-bla CHO-K1 cells • GeneBLAzer™ GPR54-NFAT-bla CHO-K1 Assay Protocol • Certificate of Analysis
Storage: The GeneBLAzer™ GPR54-NFAT-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.