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Thermo Scientific™

GeneBLAzer™ EDNRA-NFAT-bla HEK 293T Cells

Catalog number: K1726
Thermo Scientific™

GeneBLAzer™ EDNRA-NFAT-bla HEK 293T Cells

Catalog number: K1726
Catalog Number
K1726
Unit Size
2 x 106 cells
Price (USD)
8,140.00
Your Price:
Availability
***
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
K17262 x 106 cells
8,140.00
Your Price:
***
Product Overview
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GeneBLAzer™ EDNRA-NFAT-bla HEK293T cells contain the human Endothelin Type A Recpetor (EDNRA) stably integrated into the CellSensor™ NFAT-bla HEK293T cell line. CellSensor™ NFAT-bla HEK293T cells (Cat. no. K1538) contain a beta-lactamase reporter gene under control of the Nuclear Factor of Activated T-cells (NFAT) response element.

The GeneBLAzer™ EDNRA-NFAT-bla HEK293T cells are functionally validated for Z' and EC50 concentrations of ET-1. In addition, GeneBLAzer™ EDNRA-NFAT-bla HEK293T cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

The ENDRA receptor mediates signaling of endothelin proteins that regulate several critical biological processes, including development and function of blood vessels, production of certain hormones, and stimulation of cell growth and division. Defects in EDNRA-mediated signaling have been implicated in a wide range of diseases, including cancer, hypertension, and cardiovascular disorders.

For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number
NM_001957
Assay Entry
Cell-based beta lactamase reporter gene
Cell State
Dividing Cells
Detection Method
Fluorescent
For Use With (Application)
FRET
Gene Symbol
EDNRA
Population Status
Single Cell Clone Origin
Product Line
GeneBLAzer™
Reporter Gene
BLA (Beta-Lactamase)
Target Entry
EDNRA
Cell Line
293T (HEK)
System Type
GeneBLAzer™
Druggable Target
GPCRs

Contents & Storage

Contents:
K1726 GeneBLAzer™ EDNRA-NFAT-bla HEK293T cells
(LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
Includes:
• GeneBLAzer™ EDNRA-NFAT-bla HEK293T cells
• GeneBLAzer™ EDNRA-NFAT-bla HEK293T Assay Protocol
• Certificate of Analysis

Storage:
The GeneBLAzer™ EDNRA-NFAT-bla HEK293T cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

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