GeneBLAzer™ M5-NFAT-bla CHO-K1 Cells
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Thermo Scientific™

GeneBLAzer™ M5-NFAT-bla CHO-K1 Cells

GeneBLAzer™ M5-NFAT-bla CHO-K1 cells contain the human Acetylcholine (Muscarinic) Receptor 5 (M5) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cellRead more
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Catalog number K1728
Price (USD)/ Each
10,930.00
-
Add to cart
Price (USD)/ Each
10,930.00
Add to cart
GeneBLAzer™ M5-NFAT-bla CHO-K1 Cells
Catalog numberK1728
Price (USD)/ Each
10,930.00
-
Add to cart

GeneBLAzer™ M5-NFAT-bla CHO-K1 cells contain the human Acetylcholine (Muscarinic) Receptor 5 (M5) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line. CellSensor™ NFAT-bla CHO-K1 cells (Cat. No. K1534) contain a beta-lactamase reporter gene under control of the Nuclear Factor of Activated T-cells (NFAT) response element.

The GeneBLAzer™ M5-NFAT-bla CHO-K1 cells are functionally validated for Z' and EC50 concentrations of Carbachol. In addition, GeneBLAzer™ M5-NFAT-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

Muscarinic acetylcholine receptor subtype 5 (M5) has an unknown physiological relevance primarily because of low expression levels and the lack of M5 receptor-selective ligands. However, knockout studies have suggested that M5 is involved in modulation of central dopamine function and the tone of cerebral blood vessels.

For Academic pricing please login or contact us at discoverysciences@invitrogen.com.

For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession NumberBC041805.1
Assay EntryCell-based beta lactamase reporter gene
Cell StateDividing Cells
Detection MethodFluorescence
For Use With (Application)FRET
Gene SymbolCHRM5
Population StatusSingle Cell Clone Origin
Product LineGeneBLAzer™
Quantity2 x 106 Cells
Reporter GeneBLA (Beta-Lactamase)
Shipping ConditionRoom Temperature
Target EntryCHRM5, M5
Cell LineCHO-K1
System TypeGeneBLAzer™
Druggable TargetGPCR
Unit SizeEach
Contents & Storage
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.

Includes:
• GeneBLAzer™ M5-NFAT-bla CHO-K1 cells
• GeneBLAzer™ M5-NFAT-bla CHO-K1 Assay Protocol
• Certificate of Analysis

The GeneBLAzer™ M5-NFAT-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.